The final Group D matches will kick off at the Tamale Sports Stadium on Thursday with Tunisia playing Angola and Senegal going for redemption against South Africa.
This is a group in which all four teams still have mathematical chances to qualify to the quarter-final stage, depending on the results.
Being on top of the standings with four points, the joint leaders, Tunisia and Angola, will have to gun for at least a point each in their match to guarantee qualification because any slip could be disastrous as a 0-2 loss by either of them could nullify their advantage and throw the group wide open.
On a single point apiece, the Teranga Lions of Senegal and the Bafana Bafana of South Africa will like to cause surprises by clearing the final hurdle in fashionable style to undo the leaders, a feat which is possible by the current reckoning.
The Senegalese appear to have a potent armoury capable of inflicting defeat on the South Africans, who are rebuilding their team for the 2010 Word Cup that will take place in their country.
The likes of El Hadj Doiuf, Papa Buba Diop, Diomansay Camara, Henry Camara and goalkeeper Tony Sylva have enough football clout and artistry to unsettle the South Africans.
The West Africans will go all guns blazing with the hope of registering a massive win that will secure them qualification.
Brazilian World Cup winning coach, Alberto Pereira will have to delve deep into his tactical books to map out a strategy that will neutralize the Senegalese attack, while Steven Pienaar must try to seize the midfield from the rampaging Lions if South Africa must survive.
It will be a fight for leadership of the standings when Tunisia meets Angola in the other match of the group.
The Angolans who surprised the Senegalese in their last match have the zeal to play football and could be a very dangerous customer to any side.
With Manchester United-bound Manucho in reckoning for the goal king title, the Tunisians must be careful they do not allow the young striker to get on the scorers' sheet.
Roger Lemere has enough experience to guide the Carthage Eagles to the next round and he must prove that to his critics and admirers on Thursday.